
The NT scan is your pregnancy's most important first-trimester screening — a precise, painless ultrasound at 11–14 weeks that, combined with a simple blood test, calculates your baby's risk of Down syndrome and other chromosomal conditions with over 90% accuracy. At Mayflower, it is performed to the global standard set by the Fetal Medicine Foundation, London.
The nuchal translucency (NT) scan is a specialised first-trimester ultrasound that measures the small fluid-filled space at the back of your baby's neck — a measurement that, when combined with maternal age and a blood test, gives one of the most accurate first-trimester risk calculations available for chromosomal conditions. It is a screening test, not a diagnostic one: it tells you whether further investigation is recommended, not whether the baby definitely has a condition.
Chromosomal conditions: Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), Patau syndrome (Trisomy 13), and Turner syndrome. Cardiac conditions: increased NT is associated with congenital heart disease, prompting detailed fetal echocardiography later. Early structural anomalies: anencephaly, abdominal wall defects, megacystis, limb defects — visible from 11–14 weeks on the GE Voluson Signature Expert.
The actual NT thickness (the back-of-neck fluid space) is the key marker — but the scan also evaluates the nasal bone, ductus venosus flow, and tricuspid valve flow. The crown-rump length (CRL) confirms gestational age. All these markers are combined with maternal age and blood test results (PAPP-A and free beta-hCG) using the FMF (London) algorithm to give your personal risk figure.
| Best gestational window | 11 weeks 0 days to 13 weeks 6 days |
| Required CRL | 45–84 mm |
| Scan duration | 30–45 minutes |
| Combined detection rate (Down syndrome) | > 90% |
| False positive rate | 3–5% |
| Type of test | Screening — not diagnostic |
| Patient preparation | Moderately full bladder; no fasting |
| Equipment | GE Voluson Signature Expert (AI-enabled) |
| Performed by | Dr. Kunda Shahane — FMF (London) certified |
| Result discussion | Same day, with personalised counselling |
Timing is critical. The NT measurement is only reliable within a specific window — before 11 weeks the nuchal fluid is too small to measure accurately, and after 14 weeks the fluid disperses into the lymphatic system. If your dates are uncertain, an early dating scan should be done first to confirm timing.
This corresponds to a baby's crown-rump length (CRL) of 45 mm to 84 mm. The earlier in this window the scan is done, the more time you have to act on the results if further testing is needed.
A complete FMF-standard NT scan looks at five specific markers — not just the nuchal translucency thickness. Each marker contributes to the overall risk calculation. Many clinics measure NT alone; at Mayflower, every marker is evaluated systematically using FMF protocol.
A high-quality NT scan does not give you a single number from the screen. It calculates a personalised risk by combining ultrasound findings, your blood test results, and your maternal background. This is called Combined First Trimester Screening (cFTS). Dr. Kunda Shahane uses the FMF (London) algorithm — the same calculation engine used at leading centres worldwide.
The blood test (PAPP-A and free beta-hCG) is taken at 10–13 weeks. Results are combined with the NT scan markers and your maternal age using the FMF algorithm. The output is a single risk figure — for example, 1 in 5,000 (very low risk) or 1 in 80 (intermediate-to-high risk).
The NT scan is recommended for every pregnant woman, regardless of age, medical history, or how the pregnancy was conceived. It is the universal first-trimester screening — and the only opportunity to assess specific markers like nuchal translucency, which can only be measured at 11–14 weeks.
Your NT scan result is a risk figure — usually expressed as "1 in X". It is not a diagnosis. Dr. Kunda Shahane explains the result in plain language and outlines exactly what each risk category means and what your options are.
Note: Risk thresholds vary slightly between protocols. Dr. Kunda Shahane uses the FMF (London) thresholds as the basis for counselling. Risk figures are not destiny — the great majority of pregnancies with intermediate or high screening risk turn out to have a normal baby.
The whole appointment takes about an hour. The actual scan is 30–45 minutes — the rest is counselling, discussion, and answering your questions.
The NT measurement is one of the most demanding in fetal ultrasound — a 0.1 mm error in caliper placement changes the calculated risk significantly. The GE Voluson Signature Expert at Mayflower brings AI assistance specifically designed to ensure FMF-quality measurements every time.
Parents often ask whether the NT scan is still necessary if they choose NIPT — or vice versa. The honest answer: they do different things, and the strongest approach is to use both. NT scan provides essential structural information that NIPT cannot. NIPT provides higher chromosomal accuracy than ultrasound markers alone.
| What it offers | NT Scan | NIPT |
|---|---|---|
| Test type | Ultrasound + blood markers | Maternal blood test (cell-free fetal DNA) |
| When done | 11+0 to 13+6 weeks | From 10 weeks onwards |
| Down syndrome detection | > 90% (combined) | > 99% |
| Structural anomaly detection | ✅ Yes (early anatomy) | ❌ No |
| Cardiac risk indication | ✅ Yes (increased NT → fetal echo) | ❌ No |
| Twin pregnancy assessment | ✅ Yes (chorionicity + each twin) | Limited |
| Confirms gestational dating | ✅ Yes | ❌ No |
| Diagnostic certainty | Screening only | Screening only |
Dr. Kunda Shahane will recommend the best combination based on your specific situation and budget. For most families, an NT scan with combined first-trimester screening is the foundation — with NIPT added in intermediate-risk results or when extra reassurance is wanted.
In this Marathi video, Dr. Kunda Shahane discusses the importance of first trimester care, including the NT scan and combined screening. A helpful guide for parents in Vidarbha and across Maharashtra.
"An NT scan is more than a measurement. It is the first detailed conversation between a family and their pregnancy — a moment that can either be rushed and reassuring-but-empty, or careful and genuinely informative. I see this scan as a responsibility, not a routine. Every caliper placement, every Doppler waveform, every marker matters. Because the parents in front of me have come to ask whether their baby is well — and they deserve an answer built on the highest global standard, not on a shortcut. That is why FMF certification exists. And that is the standard we hold ourselves to at Mayflower."
An FMF (London)-standard NT scan, performed by Central India's first fetal medicine specialist on the GE Voluson Signature Expert. Same-day results. Compassionate counselling. Serving Nagpur, Vidarbha, and all of Central India.
Mayflower Fetal Medicine & High-Risk Pregnancy Centre, Dhantoli, Nagpur, provides fetal ultrasound, prenatal diagnosis, fetal echocardiography, Doppler studies, genetic counseling and high-risk pregnancy care under Dr. Kunda Shahane.

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Surdham Complex, Behind Silver Palace Building, 2nd Lane from Panchsheel Sq., Opp. Yashwant Stadium, Dhantoli Nagpur - 440012
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